What should I avoid while taking sumatriptan injection?

Sumatriptan can cause dizziness, weakness, or drowsiness. If you have these symptoms, do not drive a car, use machinery, or do anything where you need to be alert.

What are the possible side effects of sumatriptan injection?

Sumatriptan may cause serious side effects. See “What is the most important information I should know about sumatriptan injection?”

These serious side effects include:

• changes in color or sensation in your fingers and toes (Raynaud’s syndrome)

• stomach and intestinal problems (gastrointestinal and colonic ischemic events). Symptoms of gastrointestinal and colonic ischemic events include:

- sudden or severe stomach pain

- stomach pain after meals

- weight loss

- nausea or vomiting

- constipation or diarrhea

- bloody diarrhea

- fever

• problems with blood circulation to your legs and feet (peripheral vascular ischemia). Symptoms of peripheral vascular ischemia include:

- cramping and pain in your legs or hips

- feeling of heaviness or tightness in your leg muscles

- burning or aching pain in your feet or toes while resting

- numbness, tingling, or weakness in your legs

- cold feeling or color changes in 1 or both legs or feet

• medication overuse headaches. Some people who use too many sumatriptan injections may have worse headaches (medication overuse headache). If your

headaches get worse, your healthcare provider may decide to stop your treatment with sumatriptan.

• serotonin syndrome. Serotonin syndrome is a rare but serious problem that can happen in people using sumatriptan injection, especially if sumatriptan injection isused with antidepressant medicines called SSRIs or SNRIs.

Call your healthcare provider right away if you have any of the following symptoms of serotonin syndrome:

- mental changes such as seeing things that are not there (hallucinations), agitation, or coma

- fast heartbeat

- changes in blood pressure

- high body temperature

- tight muscles

- trouble walking

• seizures. Seizures have happened in people taking sumatriptan injection who have never had seizures before. Talk with your healthcare provider about your chance of having seizures while you take sumatriptan injection.

The most common side effects of sumatriptan injection include:

• pain or redness at your injection site

• tingling or numbness in your fingers or toes

• dizziness

• warm, hot, burning feeling to your face (flushing)

• discomfort or stiffness in your neck

• feeling weak, drowsy, or tired

Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

These are not all the possible side effects of sumatriptan injection. For more information, ask your healthcare provider or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1800-FDA-1088.

How should I store sumatriptan injection?

• Store at 25°C (77°F); excursions permitted 15°C to 30°C (59°F to 86°F) [see USP Controlled Room Temperature].

• Store your medicine away from light.

• Keep your medicine in the packaging or carrying case provided with it.

Keep sumatriptan injection and all medicines out of the reach of children.

General information about the safe and effective use of sumatriptan injection

Medicines are sometimes prescribed for purposes other than those listed in Patient Information leaflets. Do not use sumatriptan injection for a condition for which it was not prescribed. Do not give sumatriptan injection to other people, even if they have the same symptoms you have. It may harm them.

This Patient Information leaflet summarizes the most important information about sumatriptan injection. If you would like more information, talk with your healthcare provider. You can ask your healthcare provider or pharmacist for information about sumatriptan injection that is written for healthcare professionals.

For more information, call 1-888-375-3784.

What are the ingredients in sumatriptan injection?

Active ingredient: sumatriptan succinate USP

Inactive ingredients: sodium chloride, water for injection

The other brands listed are trademarks of their respective owners and are not trademarks of Dr. Reddy’s Laboratories Limited. The makers of these brands are not affiliated with and do not endorse Dr. Reddy’s Laboratories Limited or its products.

INDICATION

Sumatriptan Injection USP is a prescription medicine used to treat acute migraine headaches with or without aura and acute cluster headaches in adults who have been diagnosed with migraine or cluster headaches.